Adhesion of Candida albicans on preformed crowns used to restore primary molars: An in vitro study

Eman A. Bakhurji; Doaa M. AlEraky; Hend Alshammary; Marwah Alamoudi; Nabras Alrayes; Mohamed Hassan

doi:10.1016/j.sdentj.2024.10.001

Adhesion of Candida albicans on preformed crowns used to restore primary molars: An in vitro study

Eman A. Bakhurji^*
, Doaa M. AlEraky
, Hend Alshammary
, Marwah Alamoudi
, Nabras Alrayes
, Mohamed Hassan

^*Corresponding author for this work

Preventive Dental Sciences Department (PDS)

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Background: Assessing microbial biofilm adhesion to the restorative material's surface is a key factor in determining its success. This study aimed to compare the adhesion of Candida albicans (C. albicans) on stainless steel crowns (SSCs) versus zirconia crowns (ZCs) used for primary molars. Study design: This in vitro study involved 20 full-coverage crowns, with 10 SSCs and 10 ZCs. A fungal adhesion assay was performed to evaluate C. albicans adhesion, using colony-forming units (CFU) and cell proliferation assays. Statistics: The Wilcoxon–Mann–Whitney test was applied to compare the groups, with statistical significance set at 5 %. Results: The study revealed that SSCs had a lower mean CFU value (28.28 ± 4.557 CFU/ml) and cell proliferation rate (49.74 ± 0.4367) compared to the ZC group (30.70 ± 11.0760 CFU/ml and 74.53 ± 0.7014, respectively). However, these differences were not statistically significant. Conclusion: The findings suggest that the selection of crowns for restoring primary molars may not be influenced by C. albicans adhesion.

Original language	English
Pages (from-to)	1539-1543
Number of pages	5
Journal	Saudi Dental Journal
Volume	36
Issue number	12
DOIs	https://doi.org/10.1016/j.sdentj.2024.10.001
State	Published - Dec 2024

Keywords

Biofilm adhesion
Cell proliferation assay
CFU
Stainless steel crowns
Zirconia crowns

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10.1016/j.sdentj.2024.10.001

Cite this

@article{6c729970c3dd4ce39f82551bb9668158,

title = "Adhesion of Candida albicans on preformed crowns used to restore primary molars: An in vitro study",

abstract = "Background: Assessing microbial biofilm adhesion to the restorative material's surface is a key factor in determining its success. This study aimed to compare the adhesion of Candida albicans (C. albicans) on stainless steel crowns (SSCs) versus zirconia crowns (ZCs) used for primary molars. Study design: This in vitro study involved 20 full-coverage crowns, with 10 SSCs and 10 ZCs. A fungal adhesion assay was performed to evaluate C. albicans adhesion, using colony-forming units (CFU) and cell proliferation assays. Statistics: The Wilcoxon–Mann–Whitney test was applied to compare the groups, with statistical significance set at 5 \%. Results: The study revealed that SSCs had a lower mean CFU value (28.28 ± 4.557 CFU/ml) and cell proliferation rate (49.74 ± 0.4367) compared to the ZC group (30.70 ± 11.0760 CFU/ml and 74.53 ± 0.7014, respectively). However, these differences were not statistically significant. Conclusion: The findings suggest that the selection of crowns for restoring primary molars may not be influenced by C. albicans adhesion.",

keywords = "Biofilm adhesion, Cell proliferation assay, CFU, Stainless steel crowns, Zirconia crowns",

author = "Bakhurji, \{Eman A.\} and AlEraky, \{Doaa M.\} and Hend Alshammary and Marwah Alamoudi and Nabras Alrayes and Mohamed Hassan",

note = "Publisher Copyright: {\textcopyright} 2024 THE AUTHORS",

year = "2024",

month = dec,

doi = "10.1016/j.sdentj.2024.10.001",

language = "English",

volume = "36",

pages = "1539--1543",

journal = "Saudi Dental Journal",

issn = "1013-9052",

number = "12",

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TY - JOUR

T1 - Adhesion of Candida albicans on preformed crowns used to restore primary molars

T2 - An in vitro study

AU - Bakhurji, Eman A.

AU - AlEraky, Doaa M.

AU - Alshammary, Hend

AU - Alamoudi, Marwah

AU - Alrayes, Nabras

AU - Hassan, Mohamed

PY - 2024/12

Y1 - 2024/12

N2 - Background: Assessing microbial biofilm adhesion to the restorative material's surface is a key factor in determining its success. This study aimed to compare the adhesion of Candida albicans (C. albicans) on stainless steel crowns (SSCs) versus zirconia crowns (ZCs) used for primary molars. Study design: This in vitro study involved 20 full-coverage crowns, with 10 SSCs and 10 ZCs. A fungal adhesion assay was performed to evaluate C. albicans adhesion, using colony-forming units (CFU) and cell proliferation assays. Statistics: The Wilcoxon–Mann–Whitney test was applied to compare the groups, with statistical significance set at 5 %. Results: The study revealed that SSCs had a lower mean CFU value (28.28 ± 4.557 CFU/ml) and cell proliferation rate (49.74 ± 0.4367) compared to the ZC group (30.70 ± 11.0760 CFU/ml and 74.53 ± 0.7014, respectively). However, these differences were not statistically significant. Conclusion: The findings suggest that the selection of crowns for restoring primary molars may not be influenced by C. albicans adhesion.

AB - Background: Assessing microbial biofilm adhesion to the restorative material's surface is a key factor in determining its success. This study aimed to compare the adhesion of Candida albicans (C. albicans) on stainless steel crowns (SSCs) versus zirconia crowns (ZCs) used for primary molars. Study design: This in vitro study involved 20 full-coverage crowns, with 10 SSCs and 10 ZCs. A fungal adhesion assay was performed to evaluate C. albicans adhesion, using colony-forming units (CFU) and cell proliferation assays. Statistics: The Wilcoxon–Mann–Whitney test was applied to compare the groups, with statistical significance set at 5 %. Results: The study revealed that SSCs had a lower mean CFU value (28.28 ± 4.557 CFU/ml) and cell proliferation rate (49.74 ± 0.4367) compared to the ZC group (30.70 ± 11.0760 CFU/ml and 74.53 ± 0.7014, respectively). However, these differences were not statistically significant. Conclusion: The findings suggest that the selection of crowns for restoring primary molars may not be influenced by C. albicans adhesion.

KW - Biofilm adhesion

KW - Cell proliferation assay

KW - CFU

KW - Stainless steel crowns

KW - Zirconia crowns

UR - https://www.scopus.com/pages/publications/85207730391

U2 - 10.1016/j.sdentj.2024.10.001

DO - 10.1016/j.sdentj.2024.10.001

M3 - Article

AN - SCOPUS:85207730391

SN - 1013-9052

VL - 36

SP - 1539

EP - 1543

JO - Saudi Dental Journal

JF - Saudi Dental Journal

IS - 12

ER -

Adhesion of Candida albicans on preformed crowns used to restore primary molars: An in vitro study

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Researchers at Imam Abdulrahman Bin Faisal University Have Published New Data on Candida albicans (Adhesion of Candida albicans on preformed crowns used to restore primary molars: An in vitro study)

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Adhesion of Candida albicans on preformed crowns used to restore primary molars: An in vitro study

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Researchers at Imam Abdulrahman Bin Faisal University Have Published New Data on Candida albicans (Adhesion of Candida albicans on preformed crowns used to restore primary molars: An in vitro study)

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