Design, synthesis and antiproliferative activity against colorectal cancer cells of methyl 2-(3-(2-oxo-3-phenylquinoxalin-1(2H)-yl)propanamido)alkanoates and related compounds

Chemistry

• Apoptotic 100%
• Antiproliferative 100%
• Hydrazide 50%
• Condensation 50%
• formation 50%
• Molecular Docking 50%
• Amino Acid Ester 50%
• Azide 50%
• Discontinuous Atmospheric Pressure Interface 50%
• Hydroxylamine 50%
• Michael Reaction 50%
• Chemoselectivity 50%
• MTT Assay 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Gelatinase A 66%
• Gelatinase B 66%