IgA Vasculitis following AstraZeneca/Oxford COVID-19, case report

Nasser Alzoabi; Jamal Alqahtani; Bader Algamdi; Nada Alghamdi; Ayesha Ahmed; Gaeda Alkaltham; Tala Beidas; Omar M. Alakloby

doi:10.23750/abm.v94i6.12959

IgA Vasculitis following AstraZeneca/Oxford COVID-19, case report

Nasser Alzoabi
, Jamal Alqahtani
, Bader Algamdi
, Nada Alghamdi^*
, Ayesha Ahmed
, Gaeda Alkaltham
, Tala Beidas
, Omar M. Alakloby

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Immunoglobulin A (IgA) vasculitis, also known as Henoch–Schönlein purpura, is an immune-mediated vasculitis that affects small vessels. IgA vasculitis could be triggered by numerous conditions including infectious and non-infectious conditions. So far, few reported cases of Covid-19 vaccines related vasculitis. We report a case of IgA vasculitis after AstraZeneca/Oxford COVID-19 vaccine. A 29-year-old healthy man who developed purpuric skin lesions one week after his second AstraZeneca/Oxford COVID-19 vaccine which complicated by glomerulonephritis and gastrointestinal involvement. Skin biopsy revealed fi-brinoid necrosis and leukocytoclasia consistent with small vessel vasculitis. Due to the temporal association, AstraZeneca/Oxford COVID-19 vaccine-related IgA vasculitis would be the most likely explanation. (www.actabiomedica.it).

Original language	English
Article number	e2023074
Journal	Acta Biomedica
Volume	94
Issue number	6
DOIs	https://doi.org/10.23750/abm.v94i6.12959
State	Published - 5 Dec 2023
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

AstraZeneca/Oxford COVID-19 vaccine
IgA vasculitis
skin biopsy

Access to Document

10.23750/abm.v94i6.12959

Cite this

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title = "IgA Vasculitis following AstraZeneca/Oxford COVID-19, case report",

abstract = "Immunoglobulin A (IgA) vasculitis, also known as Henoch–Sch{\"o}nlein purpura, is an immune-mediated vasculitis that affects small vessels. IgA vasculitis could be triggered by numerous conditions including infectious and non-infectious conditions. So far, few reported cases of Covid-19 vaccines related vasculitis. We report a case of IgA vasculitis after AstraZeneca/Oxford COVID-19 vaccine. A 29-year-old healthy man who developed purpuric skin lesions one week after his second AstraZeneca/Oxford COVID-19 vaccine which complicated by glomerulonephritis and gastrointestinal involvement. Skin biopsy revealed fi-brinoid necrosis and leukocytoclasia consistent with small vessel vasculitis. Due to the temporal association, AstraZeneca/Oxford COVID-19 vaccine-related IgA vasculitis would be the most likely explanation. (www.actabiomedica.it).",

keywords = "AstraZeneca/Oxford COVID-19 vaccine, IgA vasculitis, skin biopsy",

author = "Nasser Alzoabi and Jamal Alqahtani and Bader Algamdi and Nada Alghamdi and Ayesha Ahmed and Gaeda Alkaltham and Tala Beidas and Alakloby, \{Omar M.\}",

note = "Publisher Copyright: {\textcopyright} Mattioli 1885.",

year = "2023",

month = dec,

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doi = "10.23750/abm.v94i6.12959",

language = "English",

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T1 - IgA Vasculitis following AstraZeneca/Oxford COVID-19, case report

AU - Alzoabi, Nasser

AU - Alqahtani, Jamal

AU - Algamdi, Bader

AU - Alghamdi, Nada

AU - Ahmed, Ayesha

AU - Alkaltham, Gaeda

AU - Beidas, Tala

AU - Alakloby, Omar M.

PY - 2023/12/5

Y1 - 2023/12/5

N2 - Immunoglobulin A (IgA) vasculitis, also known as Henoch–Schönlein purpura, is an immune-mediated vasculitis that affects small vessels. IgA vasculitis could be triggered by numerous conditions including infectious and non-infectious conditions. So far, few reported cases of Covid-19 vaccines related vasculitis. We report a case of IgA vasculitis after AstraZeneca/Oxford COVID-19 vaccine. A 29-year-old healthy man who developed purpuric skin lesions one week after his second AstraZeneca/Oxford COVID-19 vaccine which complicated by glomerulonephritis and gastrointestinal involvement. Skin biopsy revealed fi-brinoid necrosis and leukocytoclasia consistent with small vessel vasculitis. Due to the temporal association, AstraZeneca/Oxford COVID-19 vaccine-related IgA vasculitis would be the most likely explanation. (www.actabiomedica.it).

AB - Immunoglobulin A (IgA) vasculitis, also known as Henoch–Schönlein purpura, is an immune-mediated vasculitis that affects small vessels. IgA vasculitis could be triggered by numerous conditions including infectious and non-infectious conditions. So far, few reported cases of Covid-19 vaccines related vasculitis. We report a case of IgA vasculitis after AstraZeneca/Oxford COVID-19 vaccine. A 29-year-old healthy man who developed purpuric skin lesions one week after his second AstraZeneca/Oxford COVID-19 vaccine which complicated by glomerulonephritis and gastrointestinal involvement. Skin biopsy revealed fi-brinoid necrosis and leukocytoclasia consistent with small vessel vasculitis. Due to the temporal association, AstraZeneca/Oxford COVID-19 vaccine-related IgA vasculitis would be the most likely explanation. (www.actabiomedica.it).

KW - AstraZeneca/Oxford COVID-19 vaccine

KW - IgA vasculitis

KW - skin biopsy

UR - https://www.scopus.com/pages/publications/85178850595

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DO - 10.23750/abm.v94i6.12959

M3 - Article

C2 - 38054690

AN - SCOPUS:85178850595

SN - 0392-4203

VL - 94

JO - Acta Biomedica

JF - Acta Biomedica

IS - 6

M1 - e2023074

ER -

IgA Vasculitis following AstraZeneca/Oxford COVID-19, case report

Abstract

UN SDGs

Keywords

Access to Document

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