TY - JOUR
T1 - Polyaminophenol/Glycerol–Silver Nanohybrids
T2 - Synthesis, Characterization, and Antimicrobial Activity
AU - Al-Senani, Ghadah M.
AU - Abdelfatah, Amal
AU - Abdel-Gawad, Omayma F.
AU - Alshabanat, Mashael N.
AU - Shaban, Mohamed
AU - Al-Ghamdi, Azza
AU - Mohamed, Fatma
N1 - Publisher Copyright:
© The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2024.
PY - 2025/4
Y1 - 2025/4
N2 - This study presents an innovative method to tackle water-related health issues by leveraging the antibacterial properties of silver nanoparticles (AgNPs) conjugated with poly aminophenol-glycerol (PoAP)-G. The unique structural and morphological properties and antimicrobial workability of these hybrids are further improved by optimizing the doping level of AgNPs. (PoAP)-G and AgNPs are co-precipitated to form innovative (PoAP)-G/AgNPs hybrids with varying ratios (1:1, 1:1.5, and 1:2). Comprehensive examinations employing a range of analytical instruments reveal that the (PoAP)-G/AgNPs composite develops a wrinkled layer structure, resulting in a hollow morphology. This configuration amplifies its germicidal efficacy, rendering it potent against diverse microbial strains. A pivotal finding of the investigation is that the (PoAP)-G/AgNPs composite with a 1:2 ratio exhibits the most diminutive particle size (83.16 nm), and the utmost negative zeta potential (− 35.4 mV). Additionally, it demonstrates superior antimicrobial performance, as evidenced by considerable inhibition zones against various microorganisms, including Aspergillus fumigatus, Candida albicans ATCC 10231, Streptococcus pneumoniae ATCC 6303, Staphylococcus aureus ATCC 29213, Pseudomonas aeruginosa ATCC 27853, and Escherichia coli ATCC 25922. This hybrid material demonstrates the minimal minimum inhibitory concentration (MIC) values, signifying its pronounced efficacy in curbing microbial virulence. The findings of this study have significant implications for public health advancements and the global crusade for clean water accessibility.
AB - This study presents an innovative method to tackle water-related health issues by leveraging the antibacterial properties of silver nanoparticles (AgNPs) conjugated with poly aminophenol-glycerol (PoAP)-G. The unique structural and morphological properties and antimicrobial workability of these hybrids are further improved by optimizing the doping level of AgNPs. (PoAP)-G and AgNPs are co-precipitated to form innovative (PoAP)-G/AgNPs hybrids with varying ratios (1:1, 1:1.5, and 1:2). Comprehensive examinations employing a range of analytical instruments reveal that the (PoAP)-G/AgNPs composite develops a wrinkled layer structure, resulting in a hollow morphology. This configuration amplifies its germicidal efficacy, rendering it potent against diverse microbial strains. A pivotal finding of the investigation is that the (PoAP)-G/AgNPs composite with a 1:2 ratio exhibits the most diminutive particle size (83.16 nm), and the utmost negative zeta potential (− 35.4 mV). Additionally, it demonstrates superior antimicrobial performance, as evidenced by considerable inhibition zones against various microorganisms, including Aspergillus fumigatus, Candida albicans ATCC 10231, Streptococcus pneumoniae ATCC 6303, Staphylococcus aureus ATCC 29213, Pseudomonas aeruginosa ATCC 27853, and Escherichia coli ATCC 25922. This hybrid material demonstrates the minimal minimum inhibitory concentration (MIC) values, signifying its pronounced efficacy in curbing microbial virulence. The findings of this study have significant implications for public health advancements and the global crusade for clean water accessibility.
UR - https://www.scopus.com/pages/publications/105001073274
U2 - 10.1007/s10924-024-03331-4
DO - 10.1007/s10924-024-03331-4
M3 - Article
AN - SCOPUS:105001073274
SN - 1566-2543
VL - 33
SP - 2110
EP - 2122
JO - Journal of Polymers and the Environment
JF - Journal of Polymers and the Environment
IS - 4
ER -
