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An integrated deep learning framework leveraging NASNet and vision transformer with MixProcessing for accurate and precise diagnosis of lung diseases

  • Sajjad Saleem*
  • , Muhammad Zaheer Sajid
  • , Abida Sharif
  • , Jarrar Amjad
  • , Anwaar UlHaq
  • , Haya Aldossary
  • *Corresponding author for this work
  • Washington University of Science and Technology
  • George Mason University
  • South China University of Technology
  • Kansas State University
  • Central Queensland University

Research output: Contribution to journalArticlepeer-review

Abstract

Lung diseases such as pneumonia, tuberculosis, COVID-19, and lung cancer remain significant global health challenges that demand rapid and accurate diagnosis to improve patient outcomes. This study proposes NASNet-ViT, a novel deep learning framework that integrates the powerful convolutional feature extraction of NASNet with the global attention mechanisms of the Vision Transformer (ViT). To enhance diagnostic precision, a multi-stage preprocessing pipeline, termed MixProcessing, is introduced, combining wavelet transform decomposition, adaptive histogram equalization, and morphological filtering to improve image quality and feature clarity. The proposed NASNet-ViT model classifies lung images into five categories, normal, lung cancer, COVID-19, pneumonia, and tuberculosis achieving outstanding performance metrics: 98.9% accuracy, 0.99 sensitivity, 0.988 F1-score, and 0.985 specificity. Compared to established architectures such as MixNet-LD, D-ResNet, MobileNet, and ResNet50, NASNet-ViT demonstrates superior accuracy while maintaining a lightweight model size of only 25.6 MB and fast inference time of 12.4 seconds, making it practical for deployment in real-time, resource-constrained clinical environments. This research advances the field of medical image analysis by offering a robust and scalable AI solution capable of supporting clinicians in timely and precise lung disease diagnosis.

Original languageEnglish
Article number100394
JournalSLAS Technology
Volume38
DOIs
StatePublished - May 2026

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Deep learning
  • Diagnosis
  • Lung diseases
  • Medical image analysis
  • MixProcessing
  • NASNet-ViT
  • Vision transformer

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