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MTAS-MENA: adapting the Stroke Access Barrier Index (SABI) to enhance mechanical thrombectomy access in the Middle East and North Africa region

  • Ossama Yassin Mansour*
  • , Kaiz S. Asif
  • , Violiza Inoa
  • , Farid Aladham
  • , Ibrahim Alnaami
  • , Hosam Maher Al-Jehani
  • , Abdulrahman Alshamy
  • , Faisal Alghamdi
  • , Ozlem Aykac
  • , Mohamed Hamdy
  • , Hany Hamadani
  • , Mehdi Farhodi
  • , Mahmoud Galal
  • , Mohamed Ghorbani
  • , Erdem Gurkas
  • , Mohamed Alaa Habib
  • , Nadia Hammami
  • , Tamer Hassan
  • , Farouk Hassan
  • , Syed I. Hussain
  • Yahia Imam, Seby John, Wael Khalifa, Amina El Khamlichi, Amr Mahmoud, Ahmed Ossama, Mostafa Mahmoud, Ehab S. Mohamed, Nada Nasr, Atilla Ozcan Ozdemir, Umair Rashid, Salma Said, Abdulmonem Saied, Maher Saqqur, Khalid Sobh, Ryna Then, Gillian L.Gordon Perue, Mohammed Wasay, Hany Zaki Eldeen, Fawaz Al-Mufti, Santiago Ortega-Gutierrez, Sheila Martins, Dileep R. Yavagal, Ashfaq Shuaib
*Corresponding author for this work
  • Alexandria University
  • Ascension Medical Group Illinois
  • Semmes-Murphey Neurologic and Spine Clinic
  • Amman Specialized IR Center
  • King Khalid University
  • King Abdulaziz Medical City - Jeddah
  • King Abdullah Medical City
  • Osmangazi University
  • Ain Shams University
  • Ibn Al Nafees Hospital
  • Tabriz University of Medical Sciences
  • Al-Azhar University
  • University of Tehran
  • Dr. Lutfi Kirdar City Hospital
  • Université de Tunis El Manar
  • Cairo University
  • Cleveland Clinic Abu Dhabi
  • Weill Cornell Medicine-Qatar
  • Armed Forces Medical Complex in Maadi
  • Centre Hospitalier Universaitaire IBN Sina de Rabat
  • Tanta University
  • Lahore General Hospital
  • Military Tripoli General Hospital
  • University of Toronto
  • Cooper Medical School of Rowan University
  • University of Miami
  • Aga Khan University
  • New York Medical College
  • University of Iowa
  • Universidade Federal do Rio Grande do Sul
  • University of Alberta

Research output: Contribution to journalArticlepeer-review

Abstract

Background and purpose: We developed and preliminarily validated the Stroke Access Barrier Index (SABI), adapted from the global MTAS framework, then applied it to assess potential barriers to mechanical thrombectomy access in the MENA region. Methods: Cross-sectional survey with embedded instrument development and validation study. We surveyed 352 stroke and neurointerventional facility directors across the Middle East and North Africa (MENA) region, defined as 22 countries/territories, with responses obtained from 17 countries (March–June 2024), receiving 102 responses (29%). The SABI tool evaluates 12 attributes scored 0-3, yielding a total score from 0-36. Emergency medical services (EMS) utilization and health literacy were key measures. Results: The median SABI score for the MENA region was 18.5 (IQR: 10.0–24.0; 95% CI: 16.8–20.2), significantly lower (p < 0.001) than the global median of 22.0 (IQR: 14.0-28.0; 95% CI: 21.3–22.7). High-income countries scored 24.0, while low-income countries scored 10.0. Physical barriers (median: 4.5/9.0) and sociocultural barriers (median: 4.0/9.0) were most prominent. EMS utilization (median: 1.0) and health literacy (median: 1.0) were consistently low across all income levels. Urban facilities (median: 20.5) substantially outperformed rural facilities (median: 13.0, p < 0.001). Conclusions: The SABI provides an exploratory framework for identifying potential MT access barriers in the MENA region. While preliminary findings suggest substantial challenges (median score 18.5), these results require validation through prospective studies linking scores to actual MT utilization and patient outcomes. This initial assessment may guide hypothesis generation for future intervention studies.

Original languageEnglish
Article number1727476
JournalFrontiers in Neurology
Volume17
DOIs
StatePublished - 2026

Keywords

  • access barriers
  • health disparities
  • healthcare systems
  • mechanical thrombectomy
  • MENA region
  • stroke

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